Fig. 1 · Structure

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13-cis Acitretin-d3

Deuterated 13-cis Acitretin

13-cis Acitretin-d3 is a deuterium-labeled form of 13-cis Acitretin, which is the active metabolite of the systemic retinoid Acitretin. This compound primarily targets retinoic acid receptors and exhibits significant anti-proliferative and immunomodulatory effects. It is utilized in research related to psoriasis treatment and retinoid biology, providing insights into the pharmacokinetics and mechanisms of action of retinoids in dermatological therapies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1185241-03-5
Applications Deuterated 13-cis Acitretin
Formula C21H23D3O3
Molecular Weight 329.45
Synonyms Isoacitretin d3; Ro 13-7652 d3
SMILES
O=C(/C=C(\C=C\C=C(\C=C\C1=C(C=C(C(C)=C1C)OC([2H])([2H])[2H])C)C)C)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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