Fig. 1 · Structure
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(±)13-HDHA
DHA Oxide
(±)13-HDHA is an autoxidation product of docosahexaenoic acid (DHA) that serves as a biomarker for oxidative stress. This compound is produced during the incubation of DHA in various biological systems, including rat liver, brain, and intestinal microsomes, as well as being metabolized by freshwater hydra via 11R-lipoxygenase activity. Its role in oxidative stress research is particularly relevant in the brain and retina, where DHA is significantly abundant.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 90780-53-3 |
| Applications | DHA Oxide |
| Formula | C22H34O |
| Molecular Weight | 314.50 |
| Synonyms | (±)13-HDoHE; 13-hydroxy Docosahexaenoic acid |
| SMILES | CCC/C=C\C/C=C\C/C=C\CC(/C=C/C=C/C/C=C\CC)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.