Documents & Downloads

13-O-Desmethyl tacrolimus

Tacrolimus Metabolite

13-O-Desmethyl tacrolimus is the primary metabolite of Tacrolimus, exhibiting weak immunosuppressive activity. This compound is primarily utilized in research focused on monitoring Tacrolimus levels by assessing the ratio of 13-O-Desmethyl tacrolimus to Tacrolimus. Its role is crucial in understanding pharmacokinetics and optimizing immunosuppressive therapy in clinical settings.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
CAS Number	139958-51-3
Applications	Tacrolimus Metabolite
Formula	C₄₃H₆₇NO₁₂
Molecular Weight	789.99
Synonyms	13-DMT; 13-O-Demethyl FK 506
SMILES	CO[C@@H]1[C@@]2([H])O[C@@](C(C(N3[C@](CCCC3)([H])C(O[C@@H]([C@@H]([C@H](CC([C@@H](/C=C(C[C@@H](C1)C)\C)CC=C)=O)O)C)/C(C)=C/[C@H]4C[C@H]([C@@H](CC4)O)OC)=O)=O)=O)([C@@H](C[C@@H]2O)C)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.