Fig. 1 · Structure
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14-3-3-IN-2
14-3-3 Protein Inhibitor
14-3-3-IN-2 is a selective inhibitor of the 14-3-3 protein, exhibiting an IC50 of 15 nM. This compound effectively disrupts the interaction between 14-3-3α and aminopeptidase N, leading to a downregulation of MMP-1 mRNA levels associated with the 14-3-3α pathway. 14-3-3-IN-2 is valuable for research into cellular signaling, apoptosis, and cancer therapeutics, providing insights into the functional roles of 14-3-3 proteins in various biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 919751-10-3 |
| Applications | 14-3-3 Protein Inhibitor |
| Formula | C14H20NO5P |
| Molecular Weight | 313.29 |
| SMILES | O=C(COC1=C(P(O)(O)=O)C=CC=C1)NC2CCCCC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.