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14-Acetoxy parthenolide

Parthenolide Derivative

14-Acetoxy parthenolide is a derivative of parthenolide, primarily known for its potent anti-acute myeloid leukemia (AML) activity. This compound demonstrates significant efficacy against HL-60 and KG1a cells, with IC50 values of 2.8 µM and 6.3 µM, respectively. It serves as a valuable reagent for research focused on AML and related hematological malignancies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2064236-08-2
Applications	Parthenolide Derivative
Formula	C₁₇H₂₂O₅
Molecular Weight	306.35
SMILES	[H][C@]12O[C@]1(C)CC/C=C(CC[C@]3(C(C(O[C@@]32[H])=O)=C)[H])/COC(C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.