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(14R)-Triptolide

Anti-cancer Agent

(14R)-Triptolide is a derivative of Triptolide that acts as an anti-cancer agent by inhibiting various cancer cell lines. It demonstrates significant cytotoxicity with IC50 values ranging from 0.477 to 2.53 μM. This compound is utilized in cancer research, particularly for studying ovarian and colon cancers, making it a valuable tool for investigating potential therapeutic pathways.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	144539-79-7
Applications	Anti-cancer Agent
Formula	C₂₀H₂₄O₆
Molecular Weight	360.40
Synonyms	(14R)-PG490
SMILES	C[C@@]12[C@@]34[C@]5([C@H]([C@@]6([C@](O6)([H])[C@]3([H])O4)C(C)C)O)[C@@](C[C@@]1([H])C7=C(C(OC7)=O)CC2)([H])O5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.