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15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester

Drug Derivate

15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester is a derivative of 15-Deoxy-Δ-12,14-prostaglandin J2, a cyclopentenone prostaglandin and metabolite of PGD2. This compound acts as a selective PPARγ agonist with an EC50 of approximately 2 µM, and it also functions as a covalent agonist of PPARδ. 15-Deoxy-Δ12,14-Prostaglandin J2 promotes the differentiation of C3H10T1/2 fibroblasts into adipocytes, demonstrating an EC50 of 7 µM, making it valuable for research applications related to metabolism and obesity.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	1947405-90-4
Applications	Drug Derivate
Formula	C₂₃H₃₄O₅
Molecular Weight	390.51
SMILES	CCCCC/C=C/C=C1[C@H](C=CC\1=O)C/C=C\CCCC(OC(CO)CO)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.