Fig. 1 · Structure
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16-epi-Latrunculin B
Anticancer Agent
16-epi-Latrunculin B is an anticancer agent that primarily targets cellular actin dynamics. It demonstrates notable inhibitory effects on the proliferation of HeLa cells, with an IC50 value of 3.9 µM. Additionally, it exhibits antiviral activity against herpes simplex virus type 1 (HSV-1), with an effective dose (ED50) of 1 µg/mL, making it a valuable compound for cancer and virology research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 444911-05-1 |
| Applications | Anticancer Agent |
| Formula | C20H29NO5S |
| Molecular Weight | 395.51 |
| SMILES | O=C1SC[C@H]([C@]2(O)O[C@]3([H])CC[C@H](C)/C=C\CC/C(C)=C\C(O[C@@](C3)([H])C2)=O)N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.