Fig. 1 · Structure
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17(S)-HpDHA
Hydrolyzate
17(S)-HpDHA is an allosteric modulator targeting the 15-Lipoxygenase isoenzymes h15-LOX-1 and h15-LOX-2, derived from docosahexaenoic acid (DHA). It plays a key role in negatively regulating epoxide synthesis, thereby influencing lipid metabolism. Additionally, 17(S)-HpDHA demonstrates significant anti-aggregatory effects on platelets, with an effective concentration (EC50) of approximately 1 μM, making it a valuable reagent for research on cardiovascular and inflammatory processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 123673-33-6 |
| Applications | Hydrolyzate |
| Formula | C22H32O4 |
| Molecular Weight | 360.49 |
| SMILES | CC/C=C\C[C@@H](/C=C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O)OO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.