Fig. 1 · Structure
Documents & Downloads
18:0-22:6 DG
Diacylglycerol
18:0-22:6 DG (1-Stearoyl-2-docosahexaenoyl-sn-glycerol) is a diacylglycerol that targets RasGRP (Ras guanine nucleotide-releasing protein) with a Ki of 8.37 μM, effectively modulating the activation of MAP kinases, including ERK1/ERK2. This compound also activates protein kinase C (PKC) isoforms, which are integral to various cellular signaling pathways. Research applications of 18:0-22:6 DG encompass cancer, immunology, and metabolic disease studies, making it a versatile reagent for investigating cellular processes.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 65886-80-8 |
| Applications | Diacylglycerol |
| Formula | C43H72O5 |
| Molecular Weight | 669.03 |
| Synonyms | 1-Stearoyl-2-docosahexaenoyl-sn-glycerol |
| SMILES | CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(O[C@@H](CO)COC(CCCCCCCCCCCCCCCCC)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.