Fig. 1 · Structure
Documents & Downloads
18-Crown-6-ether
Dissociator
18-Crown-6-ether is a crown ether compound that serves as a specific dissociation agent, primarily targeting the competition for potassium ions in G-quadruplex structures. This compound disrupts the stability of G-quadruplexes, influencing various biological functions. Additionally, 18-Crown-6-ether can transport potassium and other metal ions across membranes with precision. It is also recognized for its role as a susceptibility substrate for the EmrE multi-drug efflux pump, thereby inhibiting bacterial growth. Its applications extend to microcapsule controlled release and the development of antibacterial enhancers.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 17455-13-9 |
| Applications | Dissociator |
| Formula | C12H24O6 |
| Molecular Weight | 264.32 |
| Synonyms | 18C6; 1,4,7,10,13,16-Hexaoxacyclooctadecane |
| SMILES | O1CCOCCOCCOCCOCCOCC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.