Fig. 1 · Structure
Documents & Downloads
18-Deoxyherboxidiene
Angiogenesis Inhibitor
18-Deoxyherboxidiene is a potent angiogenesis inhibitor that primarily targets SF3b, a component of the spliceosome involved in RNA splicing. This compound effectively inhibits the migration and tube formation of human umbilical vein endothelial cells (HUVECs) while demonstrating minimal cytotoxicity. 18-Deoxyherboxidiene holds significant potential for applications in cancer research, particularly in studies aimed at disrupting angiogenic processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1200128-66-0 |
| Applications | Angiogenesis Inhibitor |
| Formula | C25H42O5 |
| Molecular Weight | 422.60 |
| Synonyms | RQN-18690A |
| SMILES | C[C@]1([C@]([C@@H]([C@H](CC)OC)C)([H])O1)C[C@H](C)/C=C/C=C(C)/[C@@H]2[C@@H](C)CC[C@H](CC(O)=O)O2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.