Fig. 1 · Structure
Documents & Downloads
18-Oxocortisol
Mineralocorticoid Agonist
18-Oxocortisol is a naturally occurring mineralocorticoid agonist derived from cortisol via aldosterone synthase (CYP11B2). It plays a critical role in modulating electrolyte balance and blood pressure through its agonistic action on mineralocorticoid receptors. This compound serves as a valuable biomarker in the assessment of adrenal function, particularly in adrenal vein sampling studies. Its applications extend to research focused on adrenal pathologies and hypertension.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2410-60-8 |
| Applications | Mineralocorticoid Agonist |
| Formula | C21H28O6 |
| Molecular Weight | 376.44 |
| SMILES | O=C1CC[C@]2(C)[C@@]3([H])[C@@H](O)C[C@]4(C=O)[C@](C(CO)=O)(O)CC[C@@]4([H])[C@]3([H])CCC2=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.