19-(β-D-Glucopyranosyl)oxy-19-oxo-ent-labda-8(17),13-dien-16,15-olide

Catalog No.: A65235
NO Production Inhibitor
19-[(β-D-Glucopyranosyl)oxy]-19-oxo-ent-labda-8(17),13-dien-16,15-olide is a potent nitric oxide (NO) production inhibitor, primarily targeting lipopolysaccharide-activated macrophages. As a metabolite of Neoandrographolide, it exhibits significant anti-inflammatory properties, making it a valuable tool for research into inflammatory responses and related pathways. Its ability to modulate NO levels in immune cells supports investigations into various conditions involving excessive inflammation and immune dysregulation.
Grouped product items
Size Price Stock Qty
1mg
$115.00
In stock
5mg
$580.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description19-[(β-D-Glucopyranosyl)oxy]-19-oxo-ent-labda-8(17),13-dien-16,15-olide is a potent nitric oxide (NO) production inhibitor, primarily targeting lipopolysaccharide-activated macrophages. As a metabolite of Neoandrographolide, it exhibits significant anti-inflammatory properties, making it a valuable tool for research into inflammatory responses and related pathways. Its ability to modulate NO levels in immune cells supports investigations into various conditions involving excessive inflammation and immune dysregulation.
Product Information
Catalog NumA65235
FormulaC26H38O9
Molecular Weight494.57
CAS Number919120-78-8
SMILESC[C@@]([C@@H]1CCC2=CCOC2=O)(CCC3)[C@@](CCC1=C)([H])[C@]3(C)C(O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)CO)=O
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