Fig. 1 · Structure
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1β-Hydroxydeoxycholic acid
Cat. No.
A69735
CAS
80434-32-8
CYP3A Biomarker
1β-Hydroxydeoxycholic acid (1β-OH-DCA) is a secondary bile acid and a recognized biomarker for the CYP3A enzyme family. It is primarily generated through the metabolism of deoxycholic acid via CYP3A4 and CYP3A7 employing recombinant human CYP450 enzymes. This compound serves as an important tool in pharmacokinetic studies and the evaluation of drug metabolism, facilitating research in drug interactions and personalized medicine involving CYP3A activity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 80434-32-8 |
| Applications | CYP3A Biomarker |
| Formula | C24H40O5 |
| Molecular Weight | 408.57 |
| Synonyms | 1β-OH-DCA |
| SMILES | C[C@@]12[C@]3([H])[C@](CC[C@]1([H])C[C@@H](C[C@H]2O)O)([H])[C@@]4([H])[C@]([C@H](C3)O)([C@@](CC4)([H])[C@H](C)CCC(O)=O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.