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1O14

Ionizable Lipid

1O14 is an ionizable lipid that facilitates endosomal escape and cytosolic delivery of RNA through the formation of unstable non-bilayer structures at acidic pH. This property makes it a valuable reagent for the preparation of liposomes in RNA delivery systems. Its application supports advancements in gene therapy and mRNA vaccine development.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3117189-57-5
Applications	Ionizable Lipid
Formula	C₈₀H₁₆₆N₄O₅
Molecular Weight	1264.20
SMILES	CCCCCCCCCCCCC(CN(CCCN(CC(O)CCCCCCCCCCCC)CCCCNCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.