Fig. 1 · Structure

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(1R)-GLP-1 receptor agonist 12

GLP-1R Agonist Isomer

(1R)-GLP-1 receptor agonist 12 is an isomer targeting the GLP-1 receptor (GLP-1R). It exhibits significant agonistic activity, which can stimulate insulin secretion and enhance β-cell function. This compound is particularly relevant in diabetes research and the study of metabolic disorders, making it a valuable tool for exploring therapeutic strategies in glucose homeostasis and appetite regulation.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 2775376-51-5
Applications GLP-1R Agonist Isomer
Formula C31H31FN6O4
Molecular Weight 570.61
SMILES
C[C@@H](N1CCN(C2=CC=CC(OCC3=C(C=C(C=C3)C#N)F)=N2)CC1)C(N(C4=C5)C[C@@H]6CCO6)=NC4=CC=C5C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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