Fig. 1 · Structure
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2-(2,6-Dioxopiperidin-3-yl)-4-iodoisoindoline-1,3-dione
Thalidomide Analog
2-(2,6-Dioxopiperidin-3-yl)-4-iodoisoindoline-1,3-dione is a Thalidomide analog that features an iodine substitution on the isoindoline structure. This compound exhibits significant biological activity related to anti-inflammatory and anti-angiogenic properties. It is primarily utilized in research applications investigating the mechanisms of action of Thalidomide and its derivatives in various therapeutic contexts, particularly in cancer and autoimmune disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 959150-64-2 |
| Applications | Thalidomide Analog |
| Formula | C13H9IN2O4 |
| Molecular Weight | 384.13 |
| SMILES | O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3I)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.