Fig. 1 · Structure
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2-(2,6-Dioxopiperidin-3-yl)-5-ethynylisoindoline-1,3-dione
Cat. No.
A80504
CAS
2154356-63-3
Thalidomide Analog
2-(2,6-Dioxopiperidin-3-yl)-5-ethynylisoindoline-1,3-dione is a Thalidomide analog primarily engaged in protein degradation pathways through PROTAC technology. Exhibiting modulatory effects on the immune system and anti-angiogenic properties, this compound is instrumental in investigational studies targeting multiple myeloma and other malignancies. Its distinctive structural attributes facilitate the exploration of targeted therapies and the development of innovative drug delivery platforms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 2154356-63-3 |
| Applications | Thalidomide Analog |
| Formula | C15H10N2O4 |
| Molecular Weight | 282.25 |
| SMILES | O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(C#C)=C3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.