2′,2′-Difluorodeoxyuridine-13C,15N2 is a stable isotope-labeled compound targeting nucleotide metabolism. As the primary metabolite of Gemcitabine, it exhibits significant radiosensitizing effects in vitro, dependent on concentration and treatment schedule. Additionally, 2′,2′-Difluorodeoxyuridine induces S phase cell cycle arrest and promotes apoptosis in cancer cells, making it valuable for research into cancer therapeutics and cellular response mechanisms.
2′,2′-Difluorodeoxyuridine-13C,15N2 is a stable isotope-labeled compound targeting nucleotide metabolism. As the primary metabolite of Gemcitabine, it exhibits significant radiosensitizing effects in vitro, dependent on concentration and treatment schedule. Additionally, 2′,2′-Difluorodeoxyuridine induces S phase cell cycle arrest and promotes apoptosis in cancer cells, making it valuable for research into cancer therapeutics and cellular response mechanisms.
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