2,4-Dinitrobenzenesulfonic acid is an ecto-5'-nucleotidase (CD73) inhibitor with a Ki value of 63 μM for human enzymes and 144 μM for rat enzymes. This compound effectively inhibits the hydrolysis of adenosine monophosphate (AMP), preventing the production of adenosine. It is primarily utilized in cancer research to study the role of ecto-5'-nucleotidase in tumor biology and therapeutic resistance.
2,4-Dinitrobenzenesulfonic acid is an ecto-5'-nucleotidase (CD73) inhibitor with a Ki value of 63 μM for human enzymes and 144 μM for rat enzymes. This compound effectively inhibits the hydrolysis of adenosine monophosphate (AMP), preventing the production of adenosine. It is primarily utilized in cancer research to study the role of ecto-5'-nucleotidase in tumor biology and therapeutic resistance.
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