Fig. 1 · Structure
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2',5'-Dideoxyadenosine
Adenylyl Cyclase Inhibitor
2',5'-Dideoxyadenosine is a potent non-competitive inhibitor of adenylyl cyclase, binding to the P-site with an IC50 of 3 µM. As a nucleoside analog, it demonstrates significant antiadrenergic effects in cardiac tissues. This compound is invaluable for research in cardiovascular biology and studies investigating the modulation of intracellular signaling pathways involving cyclic AMP.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 6698-26-6 |
| Applications | Adenylyl Cyclase Inhibitor |
| Formula | C10H13N5O2 |
| Molecular Weight | 235.24 |
| SMILES | C[C@@H]1[C@H](C[C@H](N2C=NC3=C(N=CN=C32)N)O1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.