2,5-Dioxopyrrolidin-1-yl 6-bromohexanoate

Catalog No.: A94671
Biochemical Assay Reagent
2,5-Dioxopyrrolidin-1-yl 6-bromohexanoate functions as a versatile biochemical assay reagent, featuring a terminal bromide that serves as an efficient leaving group for nucleophilic substitution reactions. The incorporated NHS ester enables selective labeling of primary amines (-NH2) found in proteins, amine-modified oligonucleotides, and other amine-containing biomolecules. This reagent is particularly valuable for applications in bioconjugation and the study of protein interactions.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
Description2,5-Dioxopyrrolidin-1-yl 6-bromohexanoate functions as a versatile biochemical assay reagent, featuring a terminal bromide that serves as an efficient leaving group for nucleophilic substitution reactions. The incorporated NHS ester enables selective labeling of primary amines (-NH2) found in proteins, amine-modified oligonucleotides, and other amine-containing biomolecules. This reagent is particularly valuable for applications in bioconjugation and the study of protein interactions.
Product Information
Catalog NumA94671
FormulaC10H14BrNO4
Molecular Weight292.13
CAS Number42014-54-0
SMILESO=C(CCCCCBr)ON1C(CCC1=O)=O
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