Fig. 1 · Structure
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2-(Aminomethyl)phenol
Antioxidant
2-(Aminomethyl)phenol is a selective dicarbonyl scavenger that functions primarily as an antioxidant. It effectively scavenges free radicals and isolevuglandins (IsoLGs), playing a significant role in reducing inflammation and preventing early recurrence of atrial fibrillation. Additionally, this compound has been shown to promote efferocytosis and stabilize plaques while lowering malondialdehyde (MDA)-LDL and MDA-HDL levels in Ldlr-/- mouse models. Its utility makes it relevant for research in inflammation and cardiovascular diseases, including atherosclerosis and arrhythmias.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 932-30-9 |
| Applications | Antioxidant |
| Formula | C7H9NO |
| Molecular Weight | 123.16 |
| Synonyms | 2-Hydroxybenzylamine; o-Hydroxybenzylamine; 2-HOBA |
| SMILES | OC1=CC=CC=C1CN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.