Fig. 1 · Structure

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2'-Azido-2'-deoxyuridine

Ribonucleotide Reductase Inhibitor

2'-Azido-2'-deoxyuridine is a ribonucleotide reductase inhibitor that exhibits significant anti-cancer activity. This compound serves as a versatile click chemistry reagent due to its azide functionality, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can facilitate strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with entities featuring DBCO or BCN groups, making it valuable for a range of biochemical applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 26929-65-7
Applications Ribonucleotide Reductase Inhibitor
Formula C9H11N5O5
Molecular Weight 269.21
Synonyms N3dUrd
SMILES
O=C(C=C1)NC(N1[C@@H]([C@H](N=[N+]=[N-])[C@@H]2O)O[C@@H]2CO)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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