Fig. 1 · Structure
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2-Azido-NAD
NAD Analogues
2-Azido-NAD is a NAD+ analog that serves as a valuable tool for the study of intracellular Poly(ADP ribos)ylation (PARylation) processes. Its unique structure allows for specific labeling and visualization of PARP activity in live cells, facilitating research in cellular signaling and DNA repair mechanisms. This compound is useful for elucidating the roles of NAD+ in various biological processes and can aid in the development of therapeutic strategies targeting PARylation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 126609-61-8 |
| Applications | NAD Analogues |
| Formula | C21H26N10O14P2 |
| Molecular Weight | 704.44 |
| Synonyms | Nicotinamide 2-azidoadenine dinucleotide |
| SMILES | O[C@@H]1[C@H](O)[C@@H](COP(OP(OC[C@H]2O[C@@H](N3C4=NC(N=[N+]=[N-])=NC(N)=C4N=C3)[C@H](O)[C@@H]2O)(O)=O)([O-])=O)O[C@H]1[N+]5=CC=CC(C(N)=O)=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.