Fig. 1 · Structure
Documents & Downloads
2-Cyanoethylalsterpaullone
Alsterpaullone Derivative
2-Cyanoethylalsterpaullone is a derivative of Alsterpaullone, designed as a selective inhibitor targeting CDK1/Cyclin B and GSK-3β. It demonstrates potent inhibitory activities, with IC50 values of 0.23 nM for CDK1/Cyclin B and 0.8 nM for GSK-3β. This compound is valuable for research applications focused on cell cycle regulation and signal transduction pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 852527-97-0 |
| Applications | Alsterpaullone Derivative |
| Formula | C19H14N4O3 |
| Molecular Weight | 346.34 |
| SMILES | N#CCCC1=CC=C(NC(CC2=C3NC4=C2C=C([N+]([O-])=O)C=C4)=O)C3=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.