Fig. 1 · Structure
Documents & Downloads
2-Deoxy-2-fluoro-L-fucose
Fucosylation Inhibitor
2-Deoxy-2-fluoro-L-fucose is a potent fucosylation inhibitor that mimics L-fucose, interfering with the synthesis of GDP-fucose in mammalian cells. By inhibiting fucosylation, this compound serves as a valuable tool in cancer research, as fucosylation is recognized as a biomarker for the progression of various human cancers, including pancreatic and hepatocellular carcinoma. Its application in studies of cellular processes and tumor biology can provide insights into cancer metastasis and progression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 70763-62-1 |
| Applications | Fucosylation Inhibitor |
| Formula | C6H11FO4 |
| Molecular Weight | 166.15 |
| SMILES | O=C[C@@H](F)[C@@H]([C@@H]([C@H](C)O)O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.