Fig. 1 · Structure
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2′-Deoxy-4′-thiocytidine
Epigenetic Agent.
2′-Deoxy-4′-thiocytidine (T-dCyd) is an innovative epigenetic agent that targets DNA methylation processes. It has been shown to significantly increase the expression of the tumor suppressor gene p21. Furthermore, T-dCyd demonstrates efficacy in eradicating tumor cells in double-mutant xenograft models, making it a valuable tool for research in cancer biology and epigenetic modification studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 134111-30-1 |
| Applications | Epigenetic Agent. |
| Formula | C9H13N3O3S |
| Molecular Weight | 243.28 |
| SMILES | O=C(N=C(N)C=C1)N1[C@@H]2S[C@H](CO)[C@@H](O)C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.