Fig. 1 · Structure
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2'-Deoxyguanosine 5'-monophosphate disodium hydrate
DNA Components
2'-Deoxyguanosine 5'-monophosphate disodium hydrate (dGMP) serves as a target in studies of DNA components, particularly in assessing the photosensitizing effects of biopterins. Under UV-A radiation, pterin induces a photochemical reaction with dGMP, leading to potential DNA damage through oxidation. This interaction occurs via two primary mechanisms: hydrogen abstraction and electron transfer (type I) and the direct interaction with pterin, resulting in the formation of singlet molecular oxygen (1O2) (type II). dGMP is instrumental in elucidating the photodynamic properties of nucleotides and their reactivity in molecular biology research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 146877-98-7 |
| Applications | DNA Components |
| Formula | C10H14N5O7.H2O.2Na |
| Molecular Weight | 409.202 |
| Synonyms | 5'-Deoxyguanylic acid disodium hydrate |
| SMILES | O[C@H]1C[C@H](N2C=NC3=C2NC(N)=NC3=O)O[C@@H]1COP(O[Na])(O[Na])=O.[x].O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.