Fig. 1 · Structure
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2-Deoxyuridine-1,2,3,4,5-13C5
Stable Isotope
2-Deoxyuridine-1,2,3,4,5-13C5 is a stable isotope-labeled form of 2'-Deoxyuridine, a naturally occurring pyrimidine nucleotide. This compound plays a crucial role in nucleotide metabolism and is linked to various neurological disorders. Notably, 2'-Deoxyuridine has been shown to enhance chromosome breakage and reduce thymidylate synthase activity. It also demonstrates neuroprotective effects by decreasing microglial activation and alleviating oxidative stress in models of Alzheimer's disease, making it a valuable tool for research in neurodegeneration and related fields.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 478510-94-0 |
| Applications | Stable Isotope |
| Formula | C413C5H12N2O5 |
| Molecular Weight | 233.17 |
| SMILES | O[13C@H]1[13CH2][13C@@H](O[13C@@H]1[13CH2]O)N(C(N2)=O)C=CC2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.