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2'-Deoxyuridine 5'-monophosphate

Deoxynucleotide

2'-Deoxyuridine 5'-monophosphate (dUMP) is a deoxynucleotide that serves as a substrate for thymidylate synthase (TS), where it is reductively methylated to form dTMP (2'-deoxythymidine 5'-monophosphate). This conversion is crucial for DNA synthesis, as dTMP plays an essential role in nucleotide biosynthesis and cellular proliferation. dUMP is widely used in biochemical research to study enzyme mechanisms, DNA replication, and cell cycle regulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Substrate
CAS Number	964-26-1
Applications	Deoxynucleotide
Formula	C₉H₁₃N₂O₈P
Molecular Weight	308.18
Synonyms	dUMP
SMILES	O[C@H]1C[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COP(O)(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.