Fig. 1 · Structure
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2'-epi-2'-O-Acetylthevetin B
Cardiac Glycoside
2'-epi-2'-O-Acetylthevetin B is a cardiac glycoside derived from the seeds of Cerbera manghas L. It demonstrates significant biological activity by inhibiting cell viability, inducing apoptosis, and causing a loss of mitochondrial membrane potential in HepG2 liver cancer cells. This compound serves as a useful tool in research focused on cancer biology and the mechanisms of apoptosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 82145-55-9 |
| Applications | Cardiac Glycoside |
| Formula | C44H68O19 |
| Molecular Weight | 901.00 |
| Synonyms | GHSC-74 |
| SMILES | O[C@@]12[C@@]3([H])[C@@](CC[C@@]1([C@@H](C(CO4)=CC4=O)CC2)C)([H])[C@@]5([C@](C[C@H](CC5)O[C@H]6[C@H]([C@@H]([C@H]([C@@H](O6)C)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)CO[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)OC)OC(C)=O)([H])CC3)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.