Fig. 1 · Structure
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2'-Ethyl Simvastatin
HMGCR Inhibitor
2'-Ethyl Simvastatin is an HMG-CoA reductase inhibitor and a structural analog of Mevinolin. It effectively reduces cholesterol biosynthesis by inhibiting the rate-limiting enzyme in the mevalonate pathway. This compound has potential applications in studying lipid metabolism disorders and investigating therapeutic strategies for hyperlipidemia-related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 79902-42-4 |
| Applications | HMGCR Inhibitor |
| Formula | C23H34O5 |
| Molecular Weight | 390.51 |
| SMILES | CC(C)C(O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(O3)=O)[C@@]12[H])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.