Fig. 1 · Structure
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2'-F-Bz-dC Phosphoramidite
Oligoribonucleotide Intermediate
2'-F-Bz-dC Phosphoramidite serves as a crucial intermediate in the synthesis of oligoribonucleotides, including DNA and RNA. This compound features a phosphorothioate backbone, facilitating the development of antisense oligonucleotide analogs aimed at inducing apoptosis in cancer cells. Additionally, it can be utilized in the synthesis of antiviral agents, effectively inhibiting viral replication. This reagent is integral for advancing research in molecular biology and therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 161442-19-9 |
| Applications | Oligoribonucleotide Intermediate |
| Formula | C46H51FN5O8P |
| Molecular Weight | 851.90 |
| SMILES | COC1=CC=C(C(C2=CC=C(OC)C=C2)(OC[C@@H]3[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](F)[C@H](N4C=CC(NC(C5=CC=CC=C5)=O)=NC4=O)O3)C6=CC=CC=C6)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.