Fig. 1 · Structure
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2-Hydroxyphenylethanol
Pendrin Molecular Chaperone
2-Hydroxyphenylethanol serves as a molecular chaperone that facilitates the translocation of misfolded P123S mutant pendrin from the cytoplasm to the plasma membrane. This compound is particularly relevant for studying Pendred syndrome, providing insights into the mechanisms of protein folding and misfolding. Its ability to correct pendrin misfolding makes it a valuable tool for research focused on disorders related to ion transport and auditory function.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 7768-28-7 |
| Applications | Pendrin Molecular Chaperone |
| Formula | C8H10O2 |
| Molecular Weight | 138.17 |
| SMILES | OC=1C=CC=CC1CCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.