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2-Methoxy-5-acetoxyfuranogermacr-1(10)-en-6-one

Name: 2-Methoxy-5-acetoxyfuranogermacr-1(10)-en-6-one
Brand: Adooq Bioscience
SKU: A69910
Availability: OutOfStock

Cat. No. A69910 CAS 75412-96-3

Aromatase (CYP19) Inhibitor

2-Methoxy-5-acetoxyfuranogermacr-1(10)-en-6-one is a potent aromatase (CYP19) inhibitor, exhibiting an IC50 value of 0.21 μM against human targets. This compound is particularly relevant for research in breast cancer, providing insights into estrogen synthesis regulation and its implications in cancer progression. Its use in preclinical studies may advance the understanding of therapeutic strategies targeting estrogen-dependent tumors.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	75412-96-3
Applications	Aromatase (CYP19) Inhibitor
Formula	C₁₈H₂₄O₅
Molecular Weight	320.38
SMILES	O=C(C)OC1C(C2=C(C/C(C)=C\C(CC1C)OC)OC=C2C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.