Fig. 1 · Structure
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2-Methoxyidazoxan monohydrochloride
Alpha 2-Adrenoceptor Antagonist
2-Methoxyidazoxan monohydrochloride acts as a highly selective alpha 2-adrenoceptor antagonist, exhibiting minimal imidazoline antagonist activity. This compound demonstrates a significantly higher affinity for alpha 2D-adrenoceptors in guinea pigs (pKd 9.7) compared to alpha 2A-adrenoceptors in rabbits (pKd 8.2). 2-Methoxyidazoxan monohydrochloride is utilized in research applications to investigate the physiological roles of alpha 2-adrenoceptors and to explore potential therapeutic strategies targeting adrenergic signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 109544-45-8 |
| Applications | Alpha 2-Adrenoceptor Antagonist |
| Formula | C12H15ClN2O3 |
| Molecular Weight | 270.71 |
| Synonyms | RX821002 hydrochloride |
| SMILES | COC1(C2=NCCN2)OC3=CC=CC=C3OC1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.