Fig. 1 · Structure
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2-Methyl-5-acetylphenol
HIPK2 Binder
2-Methyl-5-acetylphenol is a hydroxylated methylacetophenone with a demonstrated binding affinity to the homeodomain-interacting protein kinase 2 (HIPK2). This compound is primarily derived from the aerial parts of Cannabis sativa subsp. sativa and serves as a valuable tool in Parkinson’s disease research. While it exhibits significant HIPK2 interaction, it does not reverse MPP+-induced neuronal cytotoxicity, making it a relevant candidate for studying neuroprotective strategies in Parkinson's pathology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 33414-49-2 |
| Applications | HIPK2 Binder |
| Formula | C9H10O2 |
| Molecular Weight | 150.17 |
| SMILES | CC1=C(C=C(C=C1)C(=O)C)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.