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2-Methyl estradiol

Anti-cancer Agent

2-Methyl estradiol is an endogenous metabolite of Estradiol that functions as an anti-cancer agent. It inhibits cell proliferation and angiogenesis, demonstrating IC50 values of 3 μM for human umbilical vein endothelial cells (HUVEC) and 2.39 μM for MCF-7 human breast cancer cells. This compound is valuable for research focused on cancer biology and therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1818-12-8
Applications	Anti-cancer Agent
Formula	C₁₉H₂₆O₂
Molecular Weight	286.41
SMILES	C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC(C)=C(O)C=C4CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.