Fig. 1 · Structure
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2-Methylvaleric acid
Short-chain Fatty acid
2-Methylvaleric acid is a branched short-chain fatty acid (SCFA) involved in the metabolism of branched-chain amino acids by gut microbiota. It has been identified as a potential biomarker for metabolic disorders, such as type 2 diabetes, where its levels are significantly decreased in the feces of diabetic models. This compound may influence host energy metabolism and inflammatory responses by acting on G protein-coupled receptors (GPCRs) or inhibiting histone deacetylases (HDACs). 2-Methylvaleric acid serves as a valuable tool for investigating gut microbe-host interactions and the pathophysiology of metabolic diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 97-61-0 |
| Applications | Short-chain Fatty acid |
| Formula | C6H12O2 |
| Molecular Weight | 116.16 |
| Synonyms | 2-Methylpentanoic acid |
| SMILES | CCCC(C)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.