Fig. 1 · Structure
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2-Nitro-5-thiocyanatobenzoic acid
Reactive Reagent
2-Nitro-5-thiocyanatobenzoic acid (NTCB) is a reactive reagent that effectively transfers its thiocyanate group to nucleophilic thiol groups. This compound is primarily utilized in biochemical research for the modification of thiol residues in proteins, facilitating the formation of S-cyano derivatives. Its high reactivity makes it a valuable tool for studying protein structure and function, as well as for probing thiol-containing biomolecules in various assays.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 30211-77-9 |
| Applications | Reactive Reagent |
| Formula | C8H4N2O4S |
| Molecular Weight | 224.20 |
| Synonyms | NTCB |
| SMILES | O=C(O)C1=CC(SC#N)=CC=C1[N+]([O-])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.