Fig. 1 · Structure
Documents & Downloads
2′-O-Methyl-5′-O-phosphonoadenylyl-(3′→5′)-guanosine TEA
Trinucleotide Cap Analogue
2'-O-Methyl-5'-O-phosphonoadenylyl-(3'→5')-guanosine TEA functions as a trinucleotide cap analogue, crucial for modulating mRNA stability and translation efficiency in eukaryotic cells. This compound enhances the bioactivity of mRNA by mimicking natural cap structures, thereby influencing gene expression and protein synthesis. It is widely utilized in molecular biology and RNA research applications for studying mRNA dynamics and developing therapeutic mRNA constructs.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2638447-50-2 |
| Applications | Trinucleotide Cap Analogue |
| Formula | C39H73N13O14P2 |
| Molecular Weight | 1010.02 |
| SMILES | O=P(O)(O)OC[C@@H]1[C@@H](OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C4=C(C(N=C(N4)N)=O)N=C3)O2)(O)=O)[C@@H](OC)[C@H](N5C6=NC=NC(N)=C6N=C5)O1.CCN(CC)CC.CCN(CC)CC.CCN(CC)CC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.