Fig. 1 · Structure

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2'-O-MOE-5-Me-C(Bz)

Nucleotide Material

2'-O-MOE-5-Me-C(Bz) is a nucleotide analog that serves as a substrate for oligonucleotide synthesis. This compound features a 2'-O-methoxyethyl modification, enhancing stability and cellular uptake while maintaining biological activity. It is widely utilized in research applications involving gene manipulation, RNA interference, and the development of therapeutic oligonucleotides.

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Specifications

Manufacturer Adooq Bioscience
Actions Substrate
CAS Number 163759-94-2
Applications Nucleotide Material
Formula C50H60N5O10P
Molecular Weight 922.01
SMILES
COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OCCOC)[C@H](N5C(N=C(NC(C6=CC=CC=C6)=O)C(C)=C5)=O)O4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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