Fig. 1 · Structure
Documents & Downloads
2'-O-MOE-U
Oligonucleotide
2'-O-MOE-U is a phosphoramidite utilized in oligonucleotide synthesis, specifically designed to modify nucleic acids. This compound enhances the stability and binding affinity of oligonucleotides, making it suitable for applications in molecular biology and therapeutic development. Its incorporation into RNA and DNA strands allows for improved resistance to nuclease degradation, aiding in the development of effective RNA-based therapeutics and gene editing technologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 163759-97-5 |
| Applications | Oligonucleotide |
| Formula | C42H53N4O10P |
| Molecular Weight | 804.86 |
| SMILES | COC(C=C1)=CC=C1C(C2=CC=C(OC)C=C2)(C3=CC=CC=C3)OC[C@H]4O[C@@H](N5C(NC(C=C5)=O)=O)[C@H](OCCOC)[C@@H]4OP(N(C(C)C)C(C)C)OCCC#N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.