Fig. 1 · Structure

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2'-OMe-Ac-C Phosphoramidite

Intermediate

2'-OMe-Ac-C Phosphoramidite is a modified phosphoramidite used as an intermediate in oligonucleotide synthesis. This compound enhances the stability and bioactivity of oligonucleotides, making it valuable for applications in molecular biology, genetic research, and therapeutic development. Its incorporation into oligonucleotides can improve resistance to nuclease degradation and alter pharmacological properties.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 199593-09-4
Applications Intermediate
Formula C42H52N5O9P
Molecular Weight 801.86
SMILES
COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OC)[C@H](N5C(N=C(NC(C)=O)C=C5)=O)O4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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