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2'-OMe-C Phosphoramidite

DNA/RNA Synthesi

2'-OMe-C Phosphoramidite is a phosphoramidite derivative utilized in the synthesis of modified oligonucleotides, specifically for RNA applications. This reagent incorporates 2'-O-methyl modifications, enhancing the stability and efficacy of RNA sequences. It is essential for various research applications, including structure-function studies and the development of RNA-based therapeutics.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	138906-72-6
Applications	DNA/RNA Synthesi
Formula	C₄₀H₅₀N₅O₈P
Molecular Weight	759.83
SMILES	NC(C=CN1[C@H]2[C@H](OC)[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(C3=CC=C(OC)C=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5)O2)=NC1=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.