Fig. 1 · Structure
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2'-OMe-dmf-G-CE-Phosphoramidite
For Oligonucleotide Synthesis
2'-OMe-dmf-G-CE-Phosphoramidite is a phosphoramidite monomer designed for oligonucleotide synthesis. This compound incorporates 2'-O-methyl modifications, enhancing the stability and solubility of the resulting oligonucleotides. It is suitable for a range of applications, including RNA studies, gene modulation, and therapeutic research. The use of this monomer facilitates the development of oligonucleotides with improved efficacy and reduced immunogenicity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 128219-77-2 |
| Applications | For Oligonucleotide Synthesis |
| Formula | C44H55N8O8P |
| Molecular Weight | 854.93 |
| SMILES | COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OC)[C@H](N5C(N=C(/N=C/N(C)C)NC6=O)=C6N=C5)O4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.