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2-Phenoxynicotinic acid

DHX8 Inhibitor

2-Phenoxynicotinic acid functions as a selective inhibitor of DHX8, an RNA helicase involved in various cellular processes including RNA metabolism and regulation. This compound exhibits key biological activity by modulating DHX8's role in gene expression and RNA splicing, making it valuable for research applications focused on understanding RNA-related mechanisms in diseases. Its oral bioavailability further supports its utility in in vivo studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	35620-71-4
Applications	DHX8 Inhibitor
Formula	C₁₂H₉NO₃
Molecular Weight	215.20
SMILES	C1=CC=C(C=C1)OC2=C(C=CC=N2)C(=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.