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2-Phosphoglyceric acid

Glycolysis Substrate

2-Phosphoglyceric acid is a key glycolytic substrate, serving as an intermediate in the conversion to phosphoenolpyruvate via the enzyme enolase. This compound has been shown to inhibit the ferroptosis pathway through the down-regulation of ACSL4 and up-regulation of GPX4, providing significant neuroprotective effects. Furthermore, 2-phosphoglyceric acid is a valuable indicator of the overall metabolic state and flux within cells, making it useful in a variety of research applications related to metabolism and cell survival.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2553-59-5
Applications	Glycolysis Substrate
Formula	C₃H₇O₇P
Molecular Weight	186.06
Synonyms	DL-2-phosphoglyceric acid
SMILES	O=C(O)C(OP(O)(O)=O)CO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.